Friday, August 27, 2010

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Lipolifting Lipofilling enriched with fat stem cells and fibroblasts. Breast augmentation

P rhyme or later the skin inevitably ends up showing the signs of aging, even when it leads a healthy lifestyle and balanced.

The aging process is associated with the formation rug and he and the thinning of the skin: decreases significantly with increasing age the natural number of so-called stem cells and fibroblasts, which are in youth numbers in the skin.

volume, stability and elasticity of the skin depend on these special cells in the skin, which also provide its constant renewal.
is also and above all thanks to them that keeps skin looking young for a long, toned and elastic: it must also be in the fibroblast production of collagen and elastin also!

An innovative and effective remedy is:

Lipolifting (lift with fat).

Picked of fat from the patient, it can now enrich stem cells and fibroblasts obtained from previous amplification (expansion). The fat is processed in this way re-injected into the areas where you want to eliminate the signs of skin aging.

The effects are usually immediate, visible already with the first session.

The new cells begin to carry out their action as soon as they are integrated into the dermis. So the appearance of the skin continues to improve.

part of a natural body process wrinkles are smoothed and the skin acquires volume and becomes more firm, youthful and fresh.

can be fairly easily made from a natural rejuvenation.

Of great importance is no safe local neovascularization induced by growth factors released from stem cells and fibroblasts which has enriched the fat injected.

E 'can perform additional processing on the same or other parts of the body.


A ome researchers have developed a new extract derived from stem cells of a particular variety of apple, cultivated for its extraordinary longevity.

This extract has demonstrated a strong ability to rejuvenate the skin, stimulating and protecting skin stem cells and increasing their lifespan.

Clinical tests confirm that when used on younger skin, significantly reduces the signs of aging by reducing wrinkles and improving firmness of the skin. The result is a skin looking young and radiant.

plant stem cells used in cosmetics are derived from the bark of Malus domestica variety Uttwiler Spatlauber originate in Switzerland.

This rare Swiss apple today grown in the U.S., has a unique compared to other varieties, not "wither" because it contains high levels of stem cells (longevity stem cells) that protect and preserve the fruit his life.



S today proposed the use of stem cell enriched fat also lipofilling of various parts of the body, including lips, buttocks and breast areas.

Let us consider now on:

Lipofilling in aesthetic and reconstructive breast surgery.

In adipose tissue, like bone marrow, There are, in addition to fat cells, multipotent stem cells that have the potential to differentiate into cells of different tissues.

When you do a normal lipofilling (also known as lipostructure) are mostly still present their own stem cells to survive and differentiate, while only partial sun seems to be the survival of fat cells.

When you provide, instead, to increase the number of stem cells injected by in vitro expansion, are then just the number of stem cells to be transferred (or induce formation of-) new capillaries (angiogenesis) contribute to a better tropism of the interested local transplantation, however, even at enormous advantage of the survival of fat cells injected with the same purpose "volumizer".

Lipofilling providing the plant is that fat cells of stem cells, has different objectives and capabilities filling, restructuring and even regeneration.

filling volume illustrates the challenges, the restructuring and regeneration is evidenced by improvements in the quality of skin and subcutaneous tissue in the case of poorly perfused tissues such as the treatment of ulcerated areas, radiodermatitis, radiation necrosis and scarring of various kinds.

Some biological aspects of transfer of adipose tissue, however, are not entirely clear and verifiable and that currently involves the inability to establish what the exact volume of the injection will achieve a certain amount of fat and consequently what the effect achieved by filling lipofilling of a single incident and the possibility of having to make repeated treatments at a later date.

Even with these limitations, it is appropriate to say that the lipofilling has enormous potential applications in plastic surgery and the breast in particular.

in the breast, the lipofilling can be very useful as a supplement and complement breast reconstruction with implants and stuff going to wrap the graft by increasing the thickness of subcutaneous tissue contributing to the less obvious the prosthesis, reducing the feeling of "cold womb" often present in the case of reconstruction, increasing the degree of ptosis with a more natural breast reconstructed

can help make it less visible in the upper quadrants of the prosthesis by reducing the so-called "ripple" and can make softer the reaction by reducing the periprosthetic capsular contracture

can be used for purposes restore the volumes may deficit after reconstruction with autologous flaps taken from the region abdominal or back

can be used for purposes restore the volumes in case of missing quadrantectomy outcomes, even if not everyone agrees on the desirability of lipofilling in these cases for the possible recurrence of the disease even after many years

can be used to correct defects and deformities that occur with development of volumetric asymmetries small to moderate in cases where the contralateral breast looks normal volume

has recently been proposed also for the total reconstruction of the breast after mastectomy, although in this case, it should be noted that certainly are take more action at a distance of several months with a reconstructive procedure that even in a small jar of udder volume, is certainly at least a year to a year and a half

can be used to increase or reinstate the hypoplastic breast as an alternative to breast augmentation with implants

75-80% of the surgeons are in favor of lipofilling as a method to improve the appearance of breast reconstruction or prosthesis prominent and visible, but believes that the lipofilling should be used with care and you still need to for further studies to increase the aesthetic breast volume.

Lipofilling has some advantages, firstly it is less invasive incisions are only those necessary to introduce the micro-cannula "Coleman" for aspiration and reinjection of fat in one surgery, liposuction is associated with increased volume, also the fat compared to dentures or artificial fillers gives a more natural look, and there is the possibility of rejection: the fat used is autologous or from the same patient, and finally the results of treatment are more durable than traditional techniques.

enriching the fat stem cells, the results are even better and more lasting, since fat stem cells, when transplanted in combination with a plant fat, increase the odds' survival of the transplanted tissue.

Based on these considerations, it is possible to consider that the lipofilling certainly interesting and important applications in plastic surgery of the breast, particularly to improve the reconstructions made with prostheses but also to reintegrate with autologous tissue reconstruction.

The use of the plant stem lipofilling implemented in cosmetic surgery as an alternative to the use of implants, however, and instead should be evaluated with caution and suggested highlighting the possibilities, but also the limitations (especially for volume) and those which may be the doubts (about one effect) related to a technique which, although promising results valid and very durable, however, remains the recently introduced, like the lipolifting (with stem cell enriched fat) and the use of which [as well as that of lipolifting (with stem cell enriched fat)] is still very sporadic, provides information still far too low to make it possible to draw up a proper budget in relation to its costs (now higher), but particularly in relation to actual benefits and their actual safety .


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